Digestive Disease Week® (DDW) 2026
The Latest
Study supports sex- and comorbidity-based cutoffs for stopping Barrett's surveillance
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by Alun Evans
“Most physicians make future surveillance decisions heavily based on perceived risk for EAC without considering … life expectancy.”
Thiopurines can be safely stopped when switching to subcutaneous infliximab, trial finds
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by Olivia Anderson
MINIMISE trial found no rise in antidrug antibodies or disease activity at 24 weeks after withdrawal.
Switching to subcutaneous infliximab may cut treatment failure in IBD
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by Bob Alaburda
Randomized trial finds 48-week treatment failure dropped from 40% to 15% after switching from IV.
Better onboarding may help GI practices retain APPs
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by Doug Brunk
Practical strategies from GI experts focus on mentorship, staged autonomy, and avoiding early burnout.
ESMR-L found noninferior to ESD in rectal NETs
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by Julie Greenbaum
Randomized trial shows comparable resection with shorter procedures and lower costs.
AI liquid biopsy flags occult metastases in ICC before surgery
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by Julia Cipriano
EXOMIC assay may identify candidates for neoadjuvant therapy and improve preoperative risk stratification.
Late post-colonoscopy cancers tied to detection rate
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by Julia Cipriano
Ten-year data suggest the protective effect of a high adenoma detection rate persists well beyond four years.
Metabolic disease burden tied to worse outcomes in untreated chronic hepatitis B
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by Alun Evans
Diabetes alone was linked to higher liver cancer risk and mortality in REAL-B cohort.
Cholangitis trial supports stopping antibiotics 24 hours after drainage
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by Noah Levine
In a 413-patient randomized trial, a single-day course matched the guideline-recommended four to seven days for clinical cure.
Nonendoscopic screening detects Barrett's esophagus in at-risk veterans without GERD
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by Julie Greenbaum
Swallowable cell-collection device showed 100% sensitivity in veterans lacking classic reflux symptoms.
AI score may boost UC trial efficiency
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by Doug Brunk
Continuous endoscopic metric may detect treatment effects with fewer patients.
Genetic risk for colorectal cancer growing, analysis shows
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by Bob Alaburda
“Genetic risk stratification may be increasingly useful in today's population, especially when applied at younger ages.”
Interventional endoscopy roughly doubles per-case emissions
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by Doug Brunk
“As climate change continues to reshape our healthcare systems, conscientious materials purchasing, optimized recycling and processing, and continual endoscopy suite audits can mitigate overall waste and reduce environmental impact.”
Dual-pathway co-antibody therapy shows promise in refractory IBD
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by Noah Levine
Dual inhibition of TNF-α and IL-23 pathways yields superior outcomes vs monotherapy in phase 2b Crohn’s and UC trials.
Largest cohort to date clarifies natural history of hereditary pancreatitis
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by Bob Alaburda
“Our results support the need for long-term follow-up of all individuals carrying pathogenic trypsinogen gene variants, not only those with chronic pain or recurrent pancreatitis.”
Higher-dose advanced therapies linked to better UC remission
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by Doug Brunk
“In UC, undertreatment can carry major consequences, including persistent inflammation, steroid exposure, hospitalization, and surgery.”
AGA president maps innovation agenda at DDW® 2026
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by Doug Brunk
Dr. Lawrence Kim called for a unified approach to innovation spanning AI, genomics, workforce development, and policy advocacy.
Physician triage changed management in nearly 1 in 4 GI referrals
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by Bob Alaburda
Specialists found that 47% of referrals were flagged as urgent or STAT, yet only 23% required care within a two-week window.
Antibiotics tied to early adenoma risk, study finds
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by Doug Brunk
A nested case-control study of nearly 24,000 patients found cumulative exposure and timing both matter.
Autoimmune hepatitis linked to significantly higher risk of extrahepatic cancers
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by Doug Brunk
“While autoimmune hepatitis is known to increase liver cancer risk, its association with cancers outside the liver remains poorly defined."
AI-assisted colonoscopy linked to higher adenoma detection
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by Doug Brunk
A real-world analysis of more than 1.5 million matched patients links AI-assisted colonoscopy to a 47% reduction in interval colorectal cancer.
Early-onset CRC deaths rising fast, analysis finds
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by Doug Brunk
“Rectal cancer is striking younger Americans earlier and killing faster."
Investigational endoscopic therapy maintains weight after GLP-1 discontinuation
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by Doug Brunk
The treatment could provide an "off-ramp for patients who either can't or don't want to be on these drugs long-term."
Late-night eating, stress tied to bowel issues
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by Doug Brunk
Meal timing “might magnify the impact of stress on the microbiome via the gut-brain axis."
